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"That's a tough question to answer, and not an easy one to answer. We're seeing some amazing results in this trial, and it's truly exciting," said Dr. David Ho, Chief of the Division Cardiology at Dana-Farber. "Many people living with heart disease, or people diabetes, are at particularly high risk of experiencing severe blood vessel blockages. Because of their age and lifestyle (and possibly their medications) these patients are at greater risk of developing dangerous blood vessel blockages. Atorvastatin seems to dramatically lower these risk of blood vessels to become blocked, and we're seeing results in just 30 percent of patients who were taking atorvastatin. That makes it the most effective drug we've ever seen for high-risk patients in an open-label comparative study with a more expensive drug we didn't know about."
"We are extremely encouraged by these results, and are eager to continue see an even greater benefit in atorvastatin patients as they advance out of the trial," added Dr. John O'Donnell, Vice President, Research and Development at Bristol-Myers Squibb. He also oversees the Phase III trial, which is examining the impact of atorvastatin on secondary prevention stroke and is currently enrolling thousands of patients.
"Although atorvastatin is a powerful drug, the cost of its delivery is challenging," said Dr. Brian Ahern, Chief Executive Officer of Novartis Pharmaceuticals. "We're pleased these results allow us to share with patients the potential benefits of atorvastatin in a manner that they can take advantage of. Whether given in the form of tablets, capsules or chewing gum, these new investigational medicines offer patients an innovative and economical way to provide essential medications that ultimately help in the prevention and treatment of heart disease."
With this approval, for the first time an atorvastatin will be available to patients with advanced heart failure who are at low risk for stroke. Patients on treatment with atorvastatin could be at lower risk of developing stroke and, because they are not prescribed the medicine on a long-term basis; could potentially stay on them for as long four years. That's Atorva 1mg $91.79 - $0.34 Per pill approximately two times longer than the current standard of care, which recommends that atorvastatin be administered for 10 years.
For more information, visit The AHA website.
This news release may contain forward-looking statements that involve risks, uncertainties and assumptions that are not all inclusive. Important factors that may cause actual results to differ materially
Buy salbutamol asthma from current estimates are described in "Risk Factors" contained elsewhere this news release, as well.
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